Hawthorn (Crataegus monogyna) and its Phytochemical Properties

Review Article





Hawthorn, Crataegus monogyna, Rosaceae, Phytochemistry


Today, due to the side effects of many synthetic drugs, attention has been drawn to directing people to natural therapeutic agents with less or no side effects. Particular attention has been paid to edible and medicinal plants, which play an important role in human nutrition and have been used in the treatment of diseases since ancient times. One of them is hawthorn. Its scientific name is Crataegus monogyna Jacq. (Hawthorn) is one of the most important edible plant species of the Rosaceae family and is also used in traditional medicine.

C. monogyna has pharmaceutical, phytochemical, functional and therapeutic properties based on numerous valuable secondary metabolites, including flavonoids, vitamin C, glycoside, anthocyanin, saponin, tannins and antioxidants. In addition, hawthorn has strengthening effects on the heart.

This review study demonstrates the potential value of hawthorn plant species as a good source of natural antioxidants and that consumption of hawthorn plant species or products can provide significant antioxidant contribution and beneficial effects in the diet. However, it makes us think that it is necessary to take into account that it may show negative effects at some points.


Nabavi SF, Habtemariam S, Ahmed T, et al. Polyphenolic Composition of Crataegus monogyna Jacq.: From Chemistry to Medical Applications. Nutrients. 2015;7(9):7708-7728. Published 2015 Sep 11. doi:10.3390/nu7095361

Keser S, Celik S, Turkoglu S, Yilmaz Ö, Turkoglu I. The investigation of some bioactive compounds and antioxidant properties of hawthorn (Crataegus monogyna subsp. monogyna Jacq). J Intercult Ethnopharmacol. 2014;3(2):51-55. doi:10.5455/jice.20140120103320

Calişkan O, Gündüz K, Serçe S, et al. Phytochemical characterization of several hawthorn (Crataegus spp.) species sampled from the Eastern Mediterranean region of Turkey. Pharmacogn Mag. 2012;8(29):16-21. doi:10.4103/0973-1296.93305

Alıç Meyvesi. Wikipedia. https://upload.wikimedia.org/wikipedia/commons/f/fb/Hawthorn_fruit.JPG (Erişim Tarihi:11.04.2023)

Yilmaz KU, Yanar M, Ercisli S, Sahiner H, Taskin T, Zengin Y. Genetic relationships among some hawthorn (Crataegus spp.) species and genotypes. Biochem Genet. 2010;48(9-10):873-878. doi:10.1007/s10528-010-9368-6

Martinelli F, Perrone A, Yousefi S, et al. Botanical, Phytochemical, Anti-Microbial and Pharmaceutical Characteristics of Hawthorn (Crataegusmonogyna Jacq.), Rosaceae. Molecules. 2021;26(23):7266. Published 2021 Nov 30. doi:10.3390/molecules26237266

Bahorun T, Trotin F, Pommery J, Vasseur J, Pinkas M. Antioxidant activities of Crataegus monogyna extracts. Planta Med. 1994;60(4):323-328. doi:10.1055/s-2006-959493

Belabdelli F, Bekhti N, Piras A, et al. Chemical composition, antioxidant and antibacterial activity of Crataegus monogyna leaves' extracts. Nat Prod Res. 2022;36(12):3234-3239. doi:10.1080/14786419.2021.1958215

Salehi S, Long SR, Proteau PJ, Filtz TM. Hawthorn (Crataegus monogyna Jacq.) extract exhibits atropine-sensitive activity in a cultured cardiomyocyte assay. J Nat Med. 2009;63(1):1-8. doi:10.1007/s11418-008-0278-4

Fong HH, Bauman JL. Hawthorn. J Cardiovasc Nurs. 2002;16(4):1-8. doi:10.1097/00005082-200207000-00002

Edwards JE, Brown PN, Talent N, Dickinson TA, Shipley PR. A review of the chemistry of the genus Crataegus. Phytochemistry. 2012;79:5-26. doi:10.1016/j.phytochem.2012.04.006

Batu A. Alıç Meyvesinin Fonksiyonel Gıda Olarak Değerlendirilmesi ve İnsan Sağlığı Bakımından Önemi. Turk.Bilimsel Derleme Derg. 2012;(2):1-5.



How to Cite

AMAÇ, Şükran, & Amaç, B. (2023). Hawthorn (Crataegus monogyna) and its Phytochemical Properties: Review Article. Acta Medica Ruha, 1(2), 158–166. https://doi.org/10.5281/zenodo.7872536