Phytochemical and Cardioprotective Properties of Hawthorn (Crataegus monogyna): An Evaluation in the Context of Cardioplegia and Myocardial Protection
Review Article
DOI:
https://doi.org/10.5281/zenodo.16784872Keywords:
Hawthorn, Crataegus monogyna, Cardioplegia, Myocardial protection, Phytochemistry, Cardiovascular surgeryAbstract
Due to the side effects of many synthetic drugs, there has been an increasing trend toward natural therapeutic agents with fewer or no adverse effects. Edible and medicinal plants, which have played an important role in human nutrition and have been used in the treatment of diseases since ancient times, have attracted considerable attention. One such plant is hawthorn (Crataegus monogyna Jacq.), an important edible species of the Rosaceae family, also widely used in traditional medicine.
Hawthorn contains flavonoids, oligomeric proanthocyanidins, vitamin C, triterpenoid saponins, and potent antioxidants, which contribute to its beneficial effects on the cardiovascular system. Recent studies have shown that hawthorn promotes coronary vasodilation, enhances myocardial oxygen distribution, and reduces oxidative stress. These properties may theoretically be beneficial in myocardial protection strategies in cardiovascular surgery—particularly during the reperfusion phase following cardioplegia.
This review examines the phytochemical profile and cardioprotective potential of hawthorn, assessing its possible contributions to myocardial protection within the scope of cardiovascular surgery and perfusion practice.
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