Investigation Of Full Blood Count Parameters, Neutrophıl Lymphocyte Ratio And Platelet Lymphocyte Ratio In Patients With Metabolic Syndrome

Research Article




Metabolic Syndrome,, Neutrophil Lymphocyte Ratio, , Platelet Lymphocyte Ratio.


Introduction: Metabolic syndrome is a fatal endocrinopathy that starts with insulin resistance and is accompanied by systemic disorders. Neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) can be a determinant in inflammation as an alternative to white blood cell count.

Aim: In this study, metabolic syndrome characterized by endothelial dysfunction, subclinical inflammation and hypercoagulability and systemic inflammation indicator; It is aimed to show the relationship between neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR).

Method: The study was carried out by retrospectively examining the demographic information and laboratory records of the patients who applied to Gaziantep Private Emek Hospital Internal Medicine Polyclinic between 01/10/2022 - 30/12/2022 for general health control or Type 2 DM follow-up. The cases were divided into 2 groups as metabolic syndrome and control group. 63 patients with metabolic syndrome and 53 healthy (control group) patients were included in the study.

Results: The neutrophil-lymphocyte ratio (NLR) was 3.44 (2.87-4.1) in the metabolic syndrome group (n=63), and the NLR was 1.81 (1.65-2.04) in the control group (n=53), and there was a statistically significant difference (p<0.001). The platelet-lymphocyte ratio (PLR) was 198 (169.5-228.5) in the metabolic syndrome group and 101 (87.7-114.2) in the control group and was statistically significant (p<0.001).

Conclusion: Metabolic syndrome, which is the cause of low-grade chronic inflammation, and NLR and PLR levels, which are easily and inexpensively accessible indicators of inflammation, were compared, and NLR and PLR levels were found to be significantly higher in the metabolic syndrome group. This result shows us that these two inflammation parameters can be used as prognostic indicators in chronic diseases.


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How to Cite

Doğantekin, A., Gören, Y., Gözel, N., Doğantekin, E., & Avcı, O. E. (2023). Investigation Of Full Blood Count Parameters, Neutrophıl Lymphocyte Ratio And Platelet Lymphocyte Ratio In Patients With Metabolic Syndrome: Research Article. Acta Medica Ruha, 1(3), 295–303.



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