Visseral Adipozite İndeksi Karpal Tünel Sendromu İçin Bir Gösterge midir?
Araştırma Makalesi
DOI:
https://doi.org/10.5281/zenodo.7890481Anahtar Kelimeler:
Karpal Tünel Sendromu, Visseral Adipozite İndeksi, Nötrofil Lenfosit OranıÖzet
Giriş: Karpal tünel sendromu (KTS), median sinirin karpal tünel içinde sıkışması ile oluşan ve en sık görülen periferik fokal mononöropatidir.
Amaç: Çalışmamızda KTS tanısı alan hastalarda, inflamasyon parametrelerini, vücut kitle indeksi (VKİ), visceral adiposity index (VAİ) değerlerini ve hastalık şiddeti ile ilişkilerini araştırmayı amaçladık.
Yöntem: Bu prospektif çalışma KTS tanısı alan 147 hasta ve 85 sağlıklı gönüllü ile yapıldı. Elektronöromiyografi sonuçlarına göre KTS şiddeti ağır, orta ve hafif olarak sınıflandırıldı. Hastaların demografik özellikleri, hemogram, inflamasyon değerleri kayıt edildi ve VKİ, VAİ ölçümleri hesaplandı.
Bulgular: KTS tanılı hastaların %78,9’u kadındı ve %26,5’nin şiddeti ağırdı. KTS tanısı alan hastaların C reactive protein (CRP), neutrophil lymphocyte ratio (NLO), trigliserid, bel çevresi, VAİ düzeyleri kontrol grubundan istatistiksel olarak anlamlı derecede daha fazlaydı (p<0,05). KTS şiddeti ağır olanlarda CRP, NLO, VKİ, VAİ ve obezite oranları, orta ve hafif olanlardan istatistiksel olarak anlamlı derecede daha fazla bulundu (p<0,05).
Sonuç:VAİ, bel çevresi, CRP, NLO oranlarının KTS’li hastalarda kontrol grubuna göre daha yüksek oranda olduğunu gösterdik. KTS tanılı hastalarda ve şiddeti ağır olanlarda VAİ ve NLR gibi göstergelerin yüksek olması, bu parametrelerin KTS geliştirme riski ve prognozu göstermede yararlı belirteçler olduklarını göstermektedir.
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