Arı Sütü Takviyesi Yoğun Egzersiz Sonrası Enerji Metabolizmasını İyileştirir
Araştırma Makalesi
DOI:
https://doi.org/10.5281/zenodo.13783567Anahtar Kelimeler:
Akut tükenme egzersizi, Arı sütü, kas adaptasyonu, Enerji metabolizmasıÖzet
Giriş: Akut tükenme egzersizi sonrası ortaya çıkan laktat birikimi, serbest radikal artışı ve enerji metabolizmasındaki düzenleyici enzimlerin aktivitesindeki değişiklikler kas adaptasyon mekanizmasını bozmakta ve kas hasarına yol açmaktadır. Hücre yenilenmesi ve terapötik etkileri ile süper gıda olarak kabul edilen arı sütü egzersiz sonrası oluşan etkileri kompanse edebilir.
Amaç: Bu çalışmada, akut tükenme egzersiz modeli oluşturulmuş Balb-c türü farelerde arı sütü takviyesinin etkileri araştırıldı.
Yöntem: Kontrol, arı sütü, akut tükenme egzersizi, akut tükenme egzersizi + arı sütü grubundan oluşan fareler rastgele dört gruba ayrıldı. Tüm gruplarda, kas adaptasyonunu düzenleyen mitokondriyal biyogenez belirteçleri Ppargc1a ve TFAM düzeyleri, aerobik ve anaerobik düzenlemede etkili olan PDHa ve Slc16a1 düzeyleri ELISA yöntemiyle analiz edildi.
Bulgular: PDHa ve Slc16a1 düzeyleri gruplar arasında istatistiksel olarak anlamlıydı (sırasıyla, p=0,024, p=0,029) ancak Ppargc1a ve TFAM düzeyleri gruplar arasında anlamlı değildi (sırasıyla, p=0,087, p=0,082). Akut tükenme egzersizi ile arı sütü takviyesi alan grupta PDHa, Slc16a1, Ppargc1a ve TFAM düzeylerinin takviye almayan gruba göre arttığı bulundu.
Sonuç: Bu bulgular akut tükenme egzersizi kaynaklı bozulmuş kas adaptasyon mekanizmasına karşı arı sütünün aerobik ve anaerobik solunum yolunu geliştirmesi/iyileştirmesi ve kas adaptasyon sürecindeki etkili potansiyelini vurgulamaktadır. Bu ümit verici sonuçlara dayanarak egzersiz fizyoloji ve spor bilimlerindeki yeni bilgileri keşfetmek için daha fazla araştırma yapılması gerekmektedir.
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