Evaluation of Preeclampsia Patients – 3 Years of Data

Research Article

Authors

DOI:

https://doi.org/10.5281/zenodo.10808636

Keywords:

Preeclampsia, Risk Factors, Disease Severity

Abstract

Introduction: Preeclampsia is the most important cause of maternal, fetal, and neonatal morbidity and mortality worldwide, affecting approximately 4% of all pregnancies.

Objective: Patients admitted to our clinic and diagnosed with non-severe preeclampsia, severe preeclampsia, HELLP syndrome, and eclampsia were retrospectively examined, and the demographic, clinical, and laboratory data obtained from these patients were compared with the diagnostic groups.

Method: A total of 156 patients, including 63 with non-severe preeclampsia, 84 with severe preeclampsia, 6 with HELLP syndrome, and 3 with eclampsia, who were followed up and treated in our center, were evaluated. Patient characteristics were classified by comparing the groups regarding delivery methods, demographic characteristics, and clinical and laboratory parameters.

Results: In terms of maternal complications, peripartum hemorrhage and placental abruption were more common in the eclampsia and severe preeclampsia groups. At the same time, DIC was more common in the patient group diagnosed with HELLP syndrome, and these results were found to be statistically significant (p<0.05). When demographic, clinical, and laboratory data were compared with whether maternal complications developed, the rate of maternal complications was found to be significantly higher in patients with elevated AST and ALT. No maternal mortality occurred in any of the patient groups.

Conclusion: The higher rate of maternal complications in patients with elevated AST and ALT suggested that follow-up of this patient group in the intensive care unit will be beneficial in reducing maternal morbidity and mortality.

References

Liu YH, Zhang YS, Chen JY, et al. Comparative effectiveness of prophylactic strategies for preeclampsia: a network meta-analysis of randomized controlled trials. Am J Obstet Gynecol. 2023;228(5):535-546. doi:10.1016/j.ajog.2022.10.014

Modzelewski J, Siarkowska I, Pajurek-Dudek J, et al. Atypical Preeclampsia before 20 Weeks of Gestation-A Systematic Review. Int J Mol Sci. 2023;24(4):3752. Published 2023 Feb 13. doi:10.3390/ijms24043752

Yagel S, Cohen SM, Admati I, et al. Expert review: preeclampsia Type I and Type II. Am J Obstet Gynecol MFM. 2023;5(12):101203. doi:10.1016/j.ajogmf.2023.101203

Magee LA, Wright D, Syngelaki A, et al. Preeclampsia Prevention by Timed Birth at Term. Hypertension. 2023;80(5):969-978. doi:10.1161/HYPERTENSIONAHA.122.20565

Yang C, Baker PN, Granger JP, Davidge ST, Tong C. Long-Term Impacts of Preeclampsia on the Cardiovascular System of Mother and Offspring. Hypertension. 2023;80(9):1821-1833. doi:10.1161/HYPERTENSIONAHA.123.21061

Büyükören A. Turfanda A., Gebelik toksikozu görülme sıklığı ve mortalitesi, Cerrahpaşa Tıp Fakültesi Dergisi 1992:23:581-585.

Yıldırım G, Güngördük K, Aslan H, Gül A, Bayraktar M, Ceylan Y. Comparison of perinatal and maternal outcomes of severe preeclampsia, eclampsia, and HELLP syndrome. J Turk Ger Gynecol Assoc. 2011;12(2):90-96. Published 2011 Jun 1. doi:10.5152/jtgga.2011.22

Shao Y, Qiu J, Huang H, et al. Pre-pregnancy BMI, gestational weight gain and risk of preeclampsia: a birth cohort study in Lanzhou, China. BMC Pregnancy Childbirth. 2017;17(1):400. Published 2017 Dec 1. doi:10.1186/s12884-017-1567-2

Zhang J, Meikle S, Trumble A. Severe maternal morbidity associated with hypertensive disorders in pregnancy in the United States. Hypertens Pregnancy. 2003;22(2):203-212. doi:10.1081/PRG-120021066

Kesim M , Erdemir M, Kaya İ ,Karlık İ , Aydemir A. Gebeliğin indüklediği hipertansiyon olgularında maternal-perinatal morbidite ve mortalite.Perinatoloji Dergisi 2001;Vol (9),No;2:116-120.

Azman G. P Dr, Kliniğimizde 2004-2009 yılları arasında doğum yapmış olan preeklampsi vakalarının retrospektif değerlendirilmesi ve MPV değerinin preeklampsi şiddetini öngörmedeki yeri, İstanbul, Haziran 2009, http://212.174.46.149/w/tez/pdf/kadin_hast/dr_.

Longo SA, Dola CP, Pridjian G. Preeclampsia and eclampsia revisited. South Med J. 2003;96(9):891-899. doi:10.1097/01.SMJ.0000084385.85123.08

Aali BS, Ghafoorian J, Mohamad-Alizadeh S. Severe preeclampsia and eclampsia in Kerman, Iran: complications and outcomes. Med Sci Monit. 2004;10(4):CR163-CR167.

Sibai BM, Mercer BM, Schiff E, Friedman SA. Aggressive versus expectant management of severe preeclampsia at 28 to 32 weeks' gestation: a randomized controlled trial. Am J Obstet Gynecol. 1994;171(3):818-822. doi:10.1016/0002-9378(94)90104-x

Oral B,Özden S, Kuyumcuoğlu U.Kliniğimizde gözlemlenen Hellp olgularının analizi. Jinekoloji ve Obstetrik Dergisi 199; 13:52–56.

Downloads

Published

2024-03-18

How to Cite

Arslan, G., Mavigök, E., & Mavigök, A. N. (2024). Evaluation of Preeclampsia Patients – 3 Years of Data: Research Article. Acta Medica Ruha, 2(1), 27–35. https://doi.org/10.5281/zenodo.10808636

Issue

Section

Research Articles